T20S (p.Thr20Ser) variant of WEE1 (Wee1-like protein kinase)
T20S (p.Thr20Ser) in WEE1 (Wee1-like protein kinase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
T20S (p.Thr20Ser) variant details
- p.Thr20Ser
- gnomAD 11-9573991-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.143
- REVEL 0.04
- CADD 17.50
- PolyPhen-2 0.00
- SIFT 0.84
- Most common in the Non-Finnish European population (allele frequency 1.1e-06)
- Structural context available
- Literature evidence available