S28L (p.Ser28Leu) variant of WEE1 (Wee1-like protein kinase)
S28L (p.Ser28Leu) in WEE1 (Wee1-like protein kinase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
S28L (p.Ser28Leu) variant details
- p.Ser28Leu
- TOPMed rs1470356965
- gnomAD rs1470356965
- Missense
- Variant Prioritization Score for Impact Estimate 0.322
- REVEL 0.05
- CADD 23.90
- PolyPhen-2 0.03
- SIFT 0.05
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available