R6Q (p.Arg6Gln) variant of WEE1 (Wee1-like protein kinase)
R6Q (p.Arg6Gln) in WEE1 (Wee1-like protein kinase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
R6Q (p.Arg6Gln) variant details
- p.Arg6Gln
- TOPMed rs1456968233
- gnomAD rs1456968233
- Missense
- Variant Prioritization Score for Impact Estimate 0.32
- REVEL 0.05
- CADD 23.80
- PolyPhen-2 0.07
- SIFT 0.11
- Most common in the East Asian population (allele frequency 7.6e-05)
- Structural context available