R22W (p.Arg22Trp) variant of WEE1 (Wee1-like protein kinase)
R22W (p.Arg22Trp) in WEE1 (Wee1-like protein kinase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
R22W (p.Arg22Trp) variant details
- p.Arg22Trp
- TOPMed rs1217796362
- gnomAD rs1217796362
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- REVEL 0.27
- CADD 26.90
- PolyPhen-2 0.79
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.00022)
- Structural context available