R22G (p.Arg22Gly) variant of WEE1 (Wee1-like protein kinase)
R22G (p.Arg22Gly) in WEE1 (Wee1-like protein kinase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
R22G (p.Arg22Gly) variant details
- p.Arg22Gly
- TOPMed rs1217796362
- gnomAD rs1217796362
- Missense
- Variant Prioritization Score for Impact Estimate 0.267
- REVEL 0.17
- CADD 23.50
- PolyPhen-2 0.30
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available