R14C (p.Arg14Cys) variant of WEE1 (Wee1-like protein kinase)
R14C (p.Arg14Cys) in WEE1 (Wee1-like protein kinase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
R14C (p.Arg14Cys) variant details
- p.Arg14Cys
- ExAC rs758698298
- gnomAD rs758698298
- Missense
- Variant Prioritization Score for Impact Estimate 0.426
- REVEL 0.21
- CADD 24.20
- PolyPhen-2 0.75
- SIFT 0.09
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.0001)
- Structural context available