R13H (p.Arg13His) variant of WEE1 (Wee1-like protein kinase)
R13H (p.Arg13His) in WEE1 (Wee1-like protein kinase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
R13H (p.Arg13His) variant details
- p.Arg13His
- gnomAD 11-9573971-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.10
- CADD 23.40
- PolyPhen-2 0.21
- SIFT 0.03
- Most common in the Ashkenazi Jewish population (allele frequency 6.3e-05)
- Structural context available
- Literature evidence available