P11S (p.Pro11Ser) variant of WEE1 (Wee1-like protein kinase)
P11S (p.Pro11Ser) in WEE1 (Wee1-like protein kinase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
P11S (p.Pro11Ser) variant details
- p.Pro11Ser
- TOPMed rs1240021878
- gnomAD rs1240021878
- Missense
- Variant Prioritization Score for Impact Estimate 0.29
- REVEL 0.03
- CADD 17.80
- PolyPhen-2 0.03
- SIFT 0.50
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available