L4M (p.Leu4Met) variant of WEE1 (Wee1-like protein kinase)
L4M (p.Leu4Met) in WEE1 (Wee1-like protein kinase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
L4M (p.Leu4Met) variant details
- p.Leu4Met
- gnomAD 11-9573943-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.125
- REVEL 0.02
- CADD 16.30
- PolyPhen-2 0.01
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 2.1e-06)
- Structural context available
- Literature evidence available