L21W (p.Leu21Trp) variant of WEE1 (Wee1-like protein kinase)
L21W (p.Leu21Trp) in WEE1 (Wee1-like protein kinase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
L21W (p.Leu21Trp) variant details
- p.Leu21Trp
- gnomAD 11-9573995-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.357
- REVEL 0.16
- CADD 28.20
- PolyPhen-2 0.86
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available