K24E (p.Lys24Glu) variant of WEE1 (Wee1-like protein kinase)
K24E (p.Lys24Glu) in WEE1 (Wee1-like protein kinase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
K24E (p.Lys24Glu) variant details
- p.Lys24Glu
- gnomAD 11-9574003-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- REVEL 0.20
- CADD 28.10
- PolyPhen-2 0.96
- SIFT 0.00
- Most common in the South Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available