G16W (p.Gly16Trp) variant of WEE1 (Wee1-like protein kinase)
G16W (p.Gly16Trp) in WEE1 (Wee1-like protein kinase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
G16W (p.Gly16Trp) variant details
- p.Gly16Trp
- gnomAD 11-9573979-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.204
- REVEL 0.06
- CADD 23.30
- PolyPhen-2 0.26
- SIFT 0.01
- Most common in the Finnish in Finland (FIN) population (allele frequency 4.2e-05)
- Structural context available
- Literature evidence available