F27I (p.Phe27Ile) variant of WEE1 (Wee1-like protein kinase)
F27I (p.Phe27Ile) in WEE1 (Wee1-like protein kinase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
F27I (p.Phe27Ile) variant details
- p.Phe27Ile
- gnomAD 11-9574012-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- REVEL 0.13
- CADD 29.30
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.1e-06)
- Structural context available
- Literature evidence available