A18T (p.Ala18Thr) variant of WEE1 (Wee1-like protein kinase)
A18T (p.Ala18Thr) in WEE1 (Wee1-like protein kinase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
A18T (p.Ala18Thr) variant details
- p.Ala18Thr
- TOPMed rs1323782444
- gnomAD rs1323782444
- Missense
- Variant Prioritization Score for Impact Estimate 0.157
- REVEL 0.03
- CADD 22.90
- PolyPhen-2 0.03
- SIFT 0.12
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available