A18S (p.Ala18Ser) variant of WEE1 (Wee1-like protein kinase)
A18S (p.Ala18Ser) in WEE1 (Wee1-like protein kinase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
A18S (p.Ala18Ser) variant details
- p.Ala18Ser
- gnomAD 11-9573985-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.146
- REVEL 0.04
- CADD 16.90
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.1e-06)
- Structural context available
- Literature evidence available