A18P (p.Ala18Pro) variant of WEE1 (Wee1-like protein kinase)
A18P (p.Ala18Pro) in WEE1 (Wee1-like protein kinase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
A18P (p.Ala18Pro) variant details
- p.Ala18Pro
- gnomAD 11-9573985-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.168
- REVEL 0.05
- CADD 23.00
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the East Asian population (allele frequency 3.8e-05)
- Structural context available
- Literature evidence available