I22V (p.Ile22Val) variant of WAS (P42768)
I22V (p.Ile22Val) in WAS (P42768) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
I22V (p.Ile22Val) variant details
- p.Ile22Val
- gnomAD rs1557006230
- Missense
- Variant Prioritization Score for Impact Estimate 0.306
- REVEL 0.33
- CADD 10.50
- PolyPhen-2 0.01
- SIFT 1.00
- Most common in the Latino/Admixed American population (allele frequency 2.8e-05)
- Structural context available