S121L (p.Ser121Leu) variant of VSIR (Q9H7M9)
S121L (p.Ser121Leu) in VSIR (Q9H7M9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
S121L (p.Ser121Leu) variant details
- p.Ser121Leu
- ExAC rs757000474
- TOPMed rs757000474
- gnomAD rs757000474
- Missense
- Variant Prioritization Score for Impact Estimate 0.26
- REVEL 0.10
- CADD 9.92
- PolyPhen-2 0.00
- SIFT 0.65
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available