R90L (p.Arg90Leu) variant of VSIR (Q9H7M9)
R90L (p.Arg90Leu) in VSIR (Q9H7M9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
R90L (p.Arg90Leu) variant details
- p.Arg90Leu
- ESP rs374460058
- ExAC rs374460058
- TOPMed rs374460058
- gnomAD rs374460058
- Missense
- Variant Prioritization Score for Impact Estimate 0.505
- REVEL 0.36
- CADD 26.90
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available