R90H (p.Arg90His) variant of VSIR (Q9H7M9)
R90H (p.Arg90His) in VSIR (Q9H7M9) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
R90H (p.Arg90His) variant details
- p.Arg90His
- rs374460058
- NCI-TCGA Cosmic COSV5644
- ESP rs374460058
- ExAC rs374460058
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.445
- REVEL 0.26
- CADD 27.30
- PolyPhen-2 0.99
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available