R87Q (p.Arg87Gln) variant of VSIR (Q9H7M9)
R87Q (p.Arg87Gln) in VSIR (Q9H7M9) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
R87Q (p.Arg87Gln) variant details
- p.Arg87Gln
- rs757499424
- ExAC rs757499424
- TOPMed rs757499424
- gnomAD rs757499424
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.183
- REVEL 0.13
- CADD 15.90
- PolyPhen-2 0.07
- SIFT 0.32
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available