R74S (p.Arg74Ser) variant of VSIR (Q9H7M9)
R74S (p.Arg74Ser) in VSIR (Q9H7M9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
R74S (p.Arg74Ser) variant details
- p.Arg74Ser
- ESP rs370678491
- ExAC rs370678491
- TOPMed rs370678491
- gnomAD rs370678491
- Missense
- Variant Prioritization Score for Impact Estimate 0.466
- REVEL 0.25
- CADD 24.50
- PolyPhen-2 0.54
- SIFT 0.10
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available