R74C (p.Arg74Cys) variant of VSIR (Q9H7M9)
R74C (p.Arg74Cys) in VSIR (Q9H7M9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
R74C (p.Arg74Cys) variant details
- p.Arg74Cys
- ESP rs370678491
- ExAC rs370678491
- TOPMed rs370678491
- gnomAD rs370678491
- Missense
- Variant Prioritization Score for Impact Estimate 0.539
- REVEL 0.33
- CADD 31.00
- PolyPhen-2 0.82
- SIFT 0.04
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available