R134C (p.Arg134Cys) variant of VSIR (Q9H7M9)
R134C (p.Arg134Cys) in VSIR (Q9H7M9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
R134C (p.Arg134Cys) variant details
- p.Arg134Cys
- ExAC rs760032960
- TOPMed rs760032960
- gnomAD rs760032960
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.22
- CADD 21.40
- PolyPhen-2 0.66
- SIFT 0.18
- Most common in the African/African-American population (allele frequency 0.00017)
- Structural context available