R116H (p.Arg116His) variant of VSIR (Q9H7M9)
R116H (p.Arg116His) in VSIR (Q9H7M9) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
R116H (p.Arg116His) variant details
- p.Arg116His
- rs200390302
- ESP rs200390302
- ExAC rs200390302
- TOPMed rs200390302
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.234
- REVEL 0.08
- CADD 6.78
- PolyPhen-2 0.01
- SIFT 0.81
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the REMAINING population (allele frequency 8.3e-05)
- Structural context available