P4R (p.Pro4Arg) variant of VSIR (Q9H7M9)
P4R (p.Pro4Arg) in VSIR (Q9H7M9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
P4R (p.Pro4Arg) variant details
- p.Pro4Arg
- ExAC rs764392258
- TOPMed rs764392258
- gnomAD rs764392258
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.10
- CADD 17.20
- PolyPhen-2 0.33
- SIFT 0.43
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available