L99R (p.Leu99Arg) variant of VSIR (Q9H7M9)
L99R (p.Leu99Arg) in VSIR (Q9H7M9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
L99R (p.Leu99Arg) variant details
- p.Leu99Arg
- gnomAD rs1935939278
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.16
- CADD 19.00
- PolyPhen-2 0.42
- SIFT 0.70
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available