L21P (p.Leu21Pro) variant of VSIR (Q9H7M9)
L21P (p.Leu21Pro) in VSIR (Q9H7M9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
L21P (p.Leu21Pro) variant details
- p.Leu21Pro
- ExAC rs761861071
- gnomAD rs761861071
- Missense
- Variant Prioritization Score for Impact Estimate 0.456
- REVEL 0.34
- CADD 25.80
- PolyPhen-2 0.37
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available