L143F (p.Leu143Phe) variant of VSIR (Q9H7M9)
L143F (p.Leu143Phe) in VSIR (Q9H7M9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
L143F (p.Leu143Phe) variant details
- p.Leu143Phe
- gnomAD rs1293145044
- Missense
- Variant Prioritization Score for Impact Estimate 0.292
- REVEL 0.25
- CADD 19.70
- PolyPhen-2 0.62
- SIFT 0.70
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available