K70R (p.Lys70Arg) variant of VSIR (Q9H7M9)
K70R (p.Lys70Arg) in VSIR (Q9H7M9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
K70R (p.Lys70Arg) variant details
- p.Lys70Arg
- ESP rs368317783
- ExAC rs368317783
- TOPMed rs368317783
- gnomAD rs368317783
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- REVEL 0.17
- CADD 25.10
- PolyPhen-2 1.00
- SIFT 0.13
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available