D65N (p.Asp65Asn) variant of VSIR (Q9H7M9)
D65N (p.Asp65Asn) in VSIR (Q9H7M9) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
D65N (p.Asp65Asn) variant details
- p.Asp65Asn
- rs370867717
- ESP rs370867717
- ExAC rs370867717
- TOPMed rs370867717
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.361
- REVEL 0.25
- CADD 22.00
- PolyPhen-2 0.15
- SIFT 0.05
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available