T8K (p.Thr8Lys) variant of VCL (Vinculin)
T8K (p.Thr8Lys) in VCL (Vinculin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
T8K (p.Thr8Lys) variant details
- p.Thr8Lys
- gnomAD rs1183306992
- Missense
- Variant Prioritization Score for Impact Estimate 0.662
- REVEL 0.57
- CADD 27.50
- PolyPhen-2 0.86
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available