T41S (p.Thr41Ser) variant of VCL (Vinculin)
T41S (p.Thr41Ser) in VCL (Vinculin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
T41S (p.Thr41Ser) variant details
- p.Thr41Ser
- gnomAD 10-73998329-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.355
- REVEL 0.09
- CADD 21.60
- PolyPhen-2 0.01
- SIFT 0.36
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available