G34S (p.Gly34Ser) variant of VCL (Vinculin)
G34S (p.Gly34Ser) in VCL (Vinculin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
G34S (p.Gly34Ser) variant details
- p.Gly34Ser
- gnomAD rs1208436782
- Missense
- Variant Prioritization Score for Impact Estimate 0.554
- REVEL 0.36
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Ashkenazi Jewish population (allele frequency 3.9e-05)
- Structural context available