E10D (p.Glu10Asp) variant of VCL (Vinculin)
E10D (p.Glu10Asp) in VCL (Vinculin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
E10D (p.Glu10Asp) variant details
- p.Glu10Asp
- gnomAD 10-73998237-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.436
- REVEL 0.40
- CADD 27.60
- PolyPhen-2 0.95
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available