V64L (p.Val64Leu) variant of UMOD (Uromodulin)
V64L (p.Val64Leu) in UMOD (Uromodulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
V64L (p.Val64Leu) variant details
- p.Val64Leu
- TOPMed rs1320992304
- gnomAD rs1320992304
- Missense
- Variant Prioritization Score for Impact Estimate 0.148
- REVEL 0.19
- CADD 0.55
- PolyPhen-2 0.10
- SIFT 0.69
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available