T86S (p.Thr86Ser) variant of UMOD (Uromodulin)
T86S (p.Thr86Ser) in UMOD (Uromodulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
T86S (p.Thr86Ser) variant details
- p.Thr86Ser
- ExAC rs765345222
- TOPMed rs765345222
- gnomAD rs765345222
- Missense
- Variant Prioritization Score for Impact Estimate 0.409
- REVEL 0.37
- CADD 10.50
- PolyPhen-2 0.03
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available