T21A (p.Thr21Ala) variant of UMOD (Uromodulin)
T21A (p.Thr21Ala) in UMOD (Uromodulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
T21A (p.Thr21Ala) variant details
- p.Thr21Ala
- ESP rs372294954
- ExAC rs372294954
- TOPMed rs372294954
- gnomAD rs372294954
- Missense
- Variant Prioritization Score for Impact Estimate 0.168
- REVEL 0.16
- CADD 0.15
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available