P87S (p.Pro87Ser) variant of UMOD (Uromodulin)
P87S (p.Pro87Ser) in UMOD (Uromodulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
P87S (p.Pro87Ser) variant details
- p.Pro87Ser
- ESP rs374642516
- ExAC rs374642516
- TOPMed rs374642516
- gnomAD rs374642516
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.36
- CADD 13.60
- PolyPhen-2 0.40
- SIFT 0.41
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available