P87A (p.Pro87Ala) variant of UMOD (Uromodulin)
P87A (p.Pro87Ala) in UMOD (Uromodulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
P87A (p.Pro87Ala) variant details
- p.Pro87Ala
- ESP rs374642516
- ExAC rs374642516
- TOPMed rs374642516
- gnomAD rs374642516
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.25
- CADD 5.07
- PolyPhen-2 0.14
- SIFT 0.52
- Most common in the Non-Finnish European population (allele frequency 3.7e-05)
- Structural context available