W5* (p.Trp5Ter) variant of UGT2B7 (UDP-glucuronosyltransferase 2B7)
W5* (p.Trp5Ter) in UGT2B7 (UDP-glucuronosyltransferase 2B7) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
W5* (p.Trp5Ter) variant details
- p.Trp5Ter
- rs754985186
- TOPMed rs754985186
- gnomAD rs754985186
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.399
- CADD 34.00
- UniProt: Variant assessed as somatic; high impact.
- Most common in the Non-Finnish European population (allele frequency 4.4e-05)
- Structural context available