V26L (p.Val26Leu) variant of UGT2B7 (UDP-glucuronosyltransferase 2B7)
V26L (p.Val26Leu) in UGT2B7 (UDP-glucuronosyltransferase 2B7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
V26L (p.Val26Leu) variant details
- p.Val26Leu
- Ensembl rs1719234527
- Missense
- Variant Prioritization Score for Impact Estimate 0.366
- REVEL 0.16
- MetaLR 0.25
- MetaSVM -0.84
- CADD 23.20
- PolyPhen-2 1.00
- SIFT 0.17
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available