T41K (p.Thr41Lys) variant of UGT2B7 (UDP-glucuronosyltransferase 2B7)
T41K (p.Thr41Lys) in UGT2B7 (UDP-glucuronosyltransferase 2B7) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
T41K (p.Thr41Lys) variant details
- p.Thr41Lys
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.254
- REVEL 0.06
- MetaLR 0.15
- MetaSVM -0.97
- CADD 13.60
- PolyPhen-2 0.89
- SIFT 0.21
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available