L63P (p.Leu63Pro) variant of UGT2B7 (UDP-glucuronosyltransferase 2B7)
L63P (p.Leu63Pro) in UGT2B7 (UDP-glucuronosyltransferase 2B7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
L63P (p.Leu63Pro) variant details
- p.Leu63Pro
- ExAC rs778794207
- TOPMed rs778794207
- gnomAD rs778794207
- Missense
- Variant Prioritization Score for Impact Estimate 0.261
- REVEL 0.19
- MetaLR 0.36
- MetaSVM -0.66
- CADD 22.20
- PolyPhen-2 0.78
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 0.00052)
- Structural context available