K4T (p.Lys4Thr) variant of UGT2B7 (UDP-glucuronosyltransferase 2B7)
K4T (p.Lys4Thr) in UGT2B7 (UDP-glucuronosyltransferase 2B7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
K4T (p.Lys4Thr) variant details
- p.Lys4Thr
- TOPMed rs1719231675
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.17
- MetaLR 0.30
- MetaSVM -0.84
- CADD 22.00
- PolyPhen-2 0.94
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available