K25T (p.Lys25Thr) variant of UGT2B7 (UDP-glucuronosyltransferase 2B7)
K25T (p.Lys25Thr) in UGT2B7 (UDP-glucuronosyltransferase 2B7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
K25T (p.Lys25Thr) variant details
- p.Lys25Thr
- gnomAD 4-69096594-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.423
- REVEL 0.31
- MetaLR 0.49
- MetaSVM -0.12
- CADD 24.90
- PolyPhen-2 0.89
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available