E32G (p.Glu32Gly) variant of UGT2B7 (UDP-glucuronosyltransferase 2B7)
E32G (p.Glu32Gly) in UGT2B7 (UDP-glucuronosyltransferase 2B7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
E32G (p.Glu32Gly) variant details
- p.Glu32Gly
- gnomAD 4-69096615-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.346
- REVEL 0.30
- MetaLR 0.26
- MetaSVM -0.75
- CADD 23.30
- PolyPhen-2 0.86
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available