R86G (p.Arg86Gly) variant of TUBB3 (Tubulin beta-3 chain)
R86G (p.Arg86Gly) in TUBB3 (Tubulin beta-3 chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
R86G (p.Arg86Gly) variant details
- p.Arg86Gly
- gnomAD rs1294173530
- Missense
- Variant Prioritization Score for Impact Estimate 0.478
- REVEL 0.54
- CADD 25.10
- PolyPhen-2 0.87
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available