R77H (p.Arg77His) variant of TUBB3 (Tubulin beta-3 chain)
R77H (p.Arg77His) in TUBB3 (Tubulin beta-3 chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
R77H (p.Arg77His) variant details
- p.Arg77His
- cosmic curated COSV59247
- gnomAD rs1216251571
- Missense
- Variant Prioritization Score for Impact Estimate 0.619
- REVEL 0.53
- CADD 25.60
- PolyPhen-2 0.10
- SIFT 0.02
- Population evidence available
- Structural context available