L84I (p.Leu84Ile) variant of TUBB3 (Tubulin beta-3 chain)
L84I (p.Leu84Ile) in TUBB3 (Tubulin beta-3 chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
L84I (p.Leu84Ile) variant details
- p.Leu84Ile
- Ensembl rs2030345780
- Missense
- Variant Prioritization Score for Impact Estimate 0.292
- REVEL 0.14
- CADD 14.60
- PolyPhen-2 0.02
- SIFT 0.54
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available